Non-profits can focus on using mediums that are already ubiquitius, such as the cell phone (ie. texting-meets-blogging, chat services). Some vloggers in the developing world are using nokia phones to post one-minute movies. (This requires, of course that the carrier have multi-media format, but many do.)

There are also many people who regularly podcast from developing countries. And the use of blogs and wikis, which are relatively bandwidth-friendly, can also be very interactive and exciting. Doing some online networking, to develop contacts with people who may be blogging or podcasting before beginning work in a country can help you to guage what is possible.

Another alternative is to invite people to submit traditional media (such as VHS), and to provide a "service" that encodes it and posts it to the web (ie, on a video blog) for them. This allows those without reliable access to the internet to participate as well.